Name Landau-Kleffner Syndrome
Related to/Also known as Acquired Epileptic Aphasia
Symptoms Landau-Kleffner Syndrome is a rare form of epilepsy that affects only children. It is characterised by severe language problems (aphasia). Symptoms may also include seizures.
Types  
Useful national contacts

Contact A Family
Freephone helpline (UK only): 0808 808 3555
Link opens in new window cafamily.org.uk

Cerebra, UK charity for children with neurological conditions
Link opens in new window http://w3.cerebra.org.uk
Telephone 01267 244200
Email This email address is being protected from spambots. You need JavaScript enabled to view it.
Find your local support:
Link opens in new window http://w3.cerebra.org.uk/help-and-information/help-in-your-area

Online resources

Landau Kleffner Syndrome (Epilepsy Action)
Link opens in new window www.epilepsy.org.uk/info/syndromes/landau-kleffner-syndrome

Landau-Kleffner Syndrome Information Page (U.S. National Institute of Neurological Disorders and Stroke)
Link opens in new window www.ninds.nih.gov/disorders/landaukleffnersyndrome/landaukleffnersyndrome.htm

Our resources The library at The Brain Charity has a range of reference resources on this condition and on a wide range of disability-related issues.

Name Leigh Syndrome
Related to/Also known as  
  • Leigh's Disease
  • Leigh's Syndrome
  • Necrotizing encephalopathy
  • Subacute Necrotizing Encephalomyelopathy (SNEM)
  • Mitochondrial disease

see also Rare Conditions

Symptoms

Leigh Syndrome is a rare, inherited, early-onset degenerative disorder with many different symptoms.

This is a disease of the mitochondria, which provide energy for nerve cells in the brain and muscles.

Types X-linked Leigh Disease
Useful national contacts The Leigh Network
Link opens in new window leighnetwork.tumblr.com
Email This email address is being protected from spambots. You need JavaScript enabled to view it.
Climb (Children Living with Inherited Metabolic Diseases)
Link opens in new window www.climb.org.uk
Freephone 0800 652 3181
The Rare Mitochondrial Disease Service for Adults and Children (NHS)
Link opens in new window www.mitochondrialncg.nhs.uk
News and events  
Online resources Leigh's Disease Information Page (U.S. National Institute for Neurological Disorders and Stroke)
Link opens in new window www.ninds.nih.gov/disorders/leighsdisease/leighsdisease.htm
Our resources The library at The Brain Charity has a range of reference resources on this condition and on a wide range of disability-related issues.

Name Leukodystrophy
Related to/Also known as Adrenoleukodystrophy (ALD)

Lorenzo's Oil disease

Symptoms The Leukodystrophies are a group of genetic disorders, which are generally diagnosed in childhood. Caused by a breakdown of the myelin sheath surrounding nerve cells in the brain. There are several forms, and the most common symptoms are a slowdown in mental and physical development
Types Metachromatic leukodystrohy
Refsum's disease
Adrenoleukodysrophy
Krabbe's disease
Phenylketonuria
Canavan disease
Pelizaeus-Merzbacher disease
Alexander's disease
Cerebrotendinous Zxanthomatosis (CTX)
Juvenile HD (also called Westphal variant or akinetic-rigid HD) develops before the age of 20, progresses rapidly, and produces muscle rigidity in which the patient moves little, if at all (akinesia).
Useful national contacts Climb National Information Centre for Metabolic Diseases
Link opens in new window www.climb.org.uk
Tel: 0800 652 3181 (Open 10am - 4pm)
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.
Online resources

Leukodystrophy Information Page (U.S. National Institute of Neurological Disorders and Stroke)
Link opens in new window www.ninds.nih.gov/disorders/leukodystrophy/leukodystrophy.htm

Our resources The library at The Brain Charity has a range of reference resources on this condition and on a wide range of disability-related issues.

Name  Lissencephaly
Related to/Also known as  
Symptoms Lissencephaly is used as an 'umbrella' term to describe a range of disorders where the whole or parts of the surface of the brain appear smooth.
Types Classical Lissencephaly

Cobblestone Lissencephaly

Useful national contacts Lissencephaly Contact Group
c/o Contact a Family
Web Link opens in new window www.cafamily.org.uk
Tel. 0808 808 3555
Online resources Lissencephaly Information page (U.S. National Institute of Neurological Disorders and Stroke)
Link opens in new window www.ninds.nih.gov/disorders/lissencephaly/lissencephaly.htm
Our resources The library at The Brain Charity has a range of reference resources on this condition and on a wide range of disability-related issues.

Name Lyme Disease
Related to/Also known as Borreliosis
Symptoms

Lyme Disease is an infectious disease caused by the bacterium Borrelia Burgdorferi. The disease is transmitted to humans by the bite of an infected tick.

If left untreated it can affect the skin, heart, nervous system and joints.

Types  
Useful national contacts Lyme Disease Action
Link opens in new window www.lymediseaseaction.org.uk
Online resources Lyme disease (NHS Choices)
Link opens in new window www.nhs.uk/conditions/lyme-disease/pages/introduction.aspx
Lyme disease (Facial Palsy UK)
Link opens in new window www.facialpalsy.org.uk/about-facial-palsy/causes-diagnoses/lyme-disease/50 >
News and events "Ignorance of tick-borne Lyme disease 'costing lives'" (BBC News, May 2013)
Link opens in new window www.bbc.co.uk/news/health-22468181
Our resources The library at The Brain Charity has a range of reference resources on this condition and on a wide range of disability-related issues.