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Memory strategies in Alzheimer’s disease: a functional (fNIRS) study

- #204 by The Brain Charity
Memory strategies in Alzheimer’s disease, MildCognitive Impairment and normal aging: a functional Near- Infrared Spectroscopy (fNIRS) study

You are being invited to participate in an experiment conducted at the Liverpool John Moores University, Byrom st, Liverpool L3 5AF.
Before you decide, it is important that you understand the purpose of this research and what it involves. Please ask the principal investigator if you have any questions or concerns regarding the study at any point.  Take time to read the following information and to decide if you want to take part or not at the research. 1.

Can I take part?
You can take part in the study if you fulfil the following criteria:
a) You are aged at least 50.
b) You are right-handed.
c) You have diagnosis of Alzheimer’s disease OR Mild Cognitive Impairment OR you have no diagnosis of dementia.
d) You do not have history of other diagnosed neurological condition (e.g. epilepsy, ictus,...).
e) You do not have history of diagnosed mental disorders (depression, anxiety, …)

What is the purpose of the study? The goals of the current study are:
a) To determine how memory strategies influence recall performance in normal and pathological ageing.
b) To establish the role of frontal brain activity in memory processes.This study may provide information on the relationship between memory strategies and neurodegeneration.

Do I have to take part?Your participation is voluntary and you are free to withdraw your consent at any time and discontinue participation in the evaluation. If you withdraw, no prejudice will be shown toward you for medical care or participation in future research studies. You will have an opportunity to ask any questions you may have about this study and all your questions have been answered to your satisfaction.

What will happen to me if I take part?
You will be asked to attend the Liverpool John Moores University – Byrom street campus, for a one time visit. The experimental procedure will consist of brief paper and computer-based tests to evaluate your memory and other thinking functions.During the computer-based test, brain activity will be recorded by functional near- infrared spectroscopy (fNIRS), a non-invasive, safe and portable neuroimaging instrument (picture below). It consists of a headband of sensors positioned on the forehead, which projects infrared light through the scalp and detects brain blood metabolism. The entire procedure will last 1 hour and you will be reimbursed for your participation with £10 in Tesco voucher.

Are there any risks / benefits involved?
We are not aware of any significant risk or discomfort associated with the neuropsychological and neuroimaging (fNIRS) measures. However, administration of memory tests can be tiring for some individuals but every effort will be made to minimize fatigue and participants will be able to take a break at any point during the testing session. Your participation in any of the tests is voluntary and you may request not to take part in any test that you anticipate might make you feel uncomfortable or uneasy.As the researcher is not a Clinical Psychologist, you won’t receive any clinical interpretation of your performance. However, findings of the study will be available at request.

Will my taking part in the study be kept confidential?
Your research records will be identified by code number only. Only the Principal Investigator will be able to link your identity to your coded sample.All information obtained during the course of this experiment will be confidential and the data collected will be retained in locked files. Your records may be shared with others in and outside the Liverpool John Moores University for research purposes, but none of this information will identify you personally. If results of this evaluation are submitted for publication, the confidentiality of your records will be maintained.

Contact details of Researcher: Deborah Talamonti, M.Sc.
email: This email address is being protected from spambots. You need JavaScript enabled to view it.

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